Physician Referred Studies

This page contains information only for particular studies that require a referral by a physician. If you were not referred to this section, then you may not qualify to participate.

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Expand a disease area below to view a list of all associated studies.

Aging +
Study of the Effects of Nitrates and Protein on your Body Composition and Muscle FunctionGENOMIC OUTCOMES OF METFORMIN Detecting Protein in the Brain Before and After DeathTesting a Questionnaire that was Developed to Better Understand a Person's Physical LimitationsUtilizing Protein During Weight Loss to Impact Physical Function (UPLIFT)IMOVE: Movement intervention for people with early-stage memory loss and their carepartners”Study of CK-2127107 to Assess the Effects on Muscle Function in Older AdultsA Study of Healthy VolunteersAIDS/HIV +
ANCHOR Study: Anal Cancer/HSIL Outcomes Research StudyPrevent Heart Disease in HIVSupporting MSM and Transgender Women in Accessing and Receiving Medical and Other Care AMC-088: Imiquimod, Fluorouracil, or Observation in Treating HIV-Positive Patients With High-Grade Anal Squamous Skin LesionsAlzheimer's +
Study of the Effects of a FDA Approved Drug on Alzheimer's DiseaseAlzheimer’s Steadfast StudyEMERGE StudyA Randomized, Double-Blind, Placebo-Controlled and Delayed-Start Study of LY3314814 in Mild Alzheimer’s Disease DementiaObservational Study Looking at the Testing of Alzheimer's Disease.Arthritis +
Weight-loss and Exercise for Communities with Arthritis in North Carolina (WE-CAN)Asthma +
To assess the efficacy and safety of QAW039 when added to existing asthma therapy in patients with uncontrolled severe asthmaBrain Injuries +
Epilepsy Medication Adherence StudyStereotactic Laser Ablation for Temporal Lobe Epilepsy (SLATE)Cancer: Brain +
Comparing Higher-Dose Radiotherapy To Standard-Dose Radiotherapy To Treat Patients With Glioblastoma Brain Tumors Study of an Investigational Drug in Cancer Patients Whose Tumors Have FGFR MutationDetermining the Competence of the Immune System over the First Year of Therapy in Patients with Malignant GliomaPilot Study of a GLioma Atkins-based Diet (GLAD) in Patients with High-Grade Astrocytoma Comprehensive Cancer Center of Wake Forest University A Study to Determine the Safety of INCB057643 in Patients with Advance MalignanciesAn Open Label Study of Study Drug (Eflornothine) with Lomustine Compared to Lomustine Alone in Patients with Anaplastic AstrocytomaCancer: Breast +
Clinical Trial of Omega-3 Pufa Dietary Supplementation in Patients with Stage 1-3 Breast CancerStudy of the Effects of Atorvastatin for Heart Problems that may Occur in Subjects Treated with ChemotherapyBenefits of Getting an MRI Before Surgery on Women with Breast CancerStudy Evaluating the Use of a New Drug with Hormone Therapy for Breast CancerComparison of Axillary Lymph Node Dissection With Axillary Radiation for Patients With Node-Positive Breast Cancer Treated With Chemotherapy Study of Alternate Treatments Before Surgery for Early Stage Breast Cancer PatientsNew Adjuvant Treatment in Patients With Germline BRCA Mutated High Risk HER2 Negative Breast Cancer Testing whether treating breast cancer metastases with surgery or high dose radiation improves survivalStudy of the Effects of Carboplatin Used with Usual Chemotherapy Drugs for Breast CancerEvaluation of High-Dose Systemic Methotrexate in Patients with Breast Cancer and Leptomeningeal MetastasisA study to compare the test test drug used with chemotherapy and trastuzumab with chemotherapy in patients with advanced HER2+ breast cancer who have received prior treatment with other medications.A phase 1, open-label, dose-escalation study to evaluate the safety and tolerability of SGN-LIV1A in patients with LIV-1-positive metastatic breast cancerA Randomized, Placebo-controlled, Double-blind, Multicenter Phase 2 Study of Atezolizumab With or Without Entinostat in Patients with Advanced Triple Negative Breast Cancer, with a Phase 1b Lead in PhaseCancer: Gastrointestinal (GI) +
Liver Research RegistryClinical Trial in Patients with Advanced Bile Duct CancersStudy Looking at a Different Treatment for Colon CancerA Study of the Test Drug (Ibrutinib) Combined with Stand of Care Medicine for Advanced Kidney, Bladder, Stomach and Colon cancer.A clinical study to evaluate 2 different test drugs combined with Sorafenib as the standard of care in the treatment of Liver cell cancer.Analysis of Genomic DNA from your Biopsy or Tissue Samples to Identify Genetic Variations that may Guide Cancer Therapy (Precision Medicine Trial)PROGRAMS TO SUPPORT YOU DURING CHEMOTHERAPY (PRO-YOU)Safety and Immunologic Activity of Multiple Infusions of APN401Testing an investigational drug with standard treatment before surgery for rectal cancer.Mapping to Guide Self-Management in Cancer Survivors Cancer: Genitourinary +
Study of an Experimental Drug or Combination of Drugs to Treat Prostate CancerStudy of tissue from bladder biopsy to determine the best treatmentStudy the Effects of IL7 (An Experimental Agent) on Patients with Prostate CancerA Study for a New Treatment of Non-Muscle Invasive Bladder CancerStudy of the Effects of FDA Approved Drugs Used Together in Men with Prostate Cancer Observational Study of Patients With Castration-Resistant Prostate CancerStudy of Low-Dose Paclitaxel with Pembrolizumab in Platinum-Refractory Urothelial CarcinomaA Study to Determine the Safety of PRN1371 in Patients with Advanced Solid Tumors in Squamous Cell Lung Cancer and Bladder CancerA Study to Determine the Safety and Efficacy of Atezolizumab in Patients with Urothelial Carcinoma (bladder cancer) after Surgery A Phase III study of ODM–201 versus placebo in addition to standard androgen deprivation therapy and docetaxel in patients with metastatic hormone–sensitive prostate cancerA Study to Determine if Enzalutamide can Delay Prostate Cancer Progression Verses Active SurveillenceA study testing the effectiveness, safety and tolerability with increasing doses of study drug Varlilumab combined with Nivolumab in advanced cancer that does not respond to treatment.Home-Based Exercise Intervention Program for Patients with Prostate CacncerCancer: Gynecology +
Pelvic Irradiation w/without Weekly Cisplatin UterineStudy to see if chemotherapy and radiation therapy improves survival in patients with cervical cancerStudy to see how chemotherapy and radiation effect your cancer of the vulvaComparison of Treatment for Endometrial CancerTreatment for patients with a stromal tumor of the ovaryStudy of Carboplatin/Paclitaxel With or Without Concurrent and Continuation Maintenance Veliparib (PARP inhibitor) in Subjects with Previously Untreated Stages III or IV High-Grade Serous Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal CancerStudy comparing single-agent olaparib or in combination with cediranib to standard platinum-based chemotherapy in women with recurrent platinum-sensitive ovarian, fallopian tube, or primary peritoneal cancerTesting the use of a single drug (olaparib) or the combination of two drugs (cediranib and olaparib) compared to the usual chemotherapy for women with platinum sensitive ovarian, fallopian tube, or primary peritoneal cancerCancer: Head Neck +
Smoking Cessation In Patients With Squamous Cell Cancer Of The Head And Neck Undergoing Radiation Therapy With Or Without ChemotherapyMEDI4736 Alone or in Combination with Tremelimumab versus Standard of Care in the Treatment of First-line Recurrent or Metastatic Squamous Cell Head and Neck Cancer PatientsTrial of the Effects of Intravenous GC4419 on the Incidence and Duration of Severe Oral Mucositis (OM) in Patients with Locally Advanced, Non-Metastatic Squamous Cell Carcinoma of the Oral Cavity or Oropharynx.A Study to Evaluate the difference between the Standard of Care Chemo-radiotherapy and the Standard of Care Chemo-radiotherapy plus the drug Avelumab.Cancer: Hematologic +
Research Tissue Bank for people with Myeloproliferative Disorders (MPD)Investigating the Importance of Bioelectrical Impedance Phase Angle in Adults Treated for Newly Diagnosed Acute LeukemiaTreatment with an experimental drug in patients with newly diagnosed Acute Lymphoblastic Leukemia. Study of an experimental drug for T-Cell Non-Hodgkin or Classic Hodgkin LymphomaStudy for patients having a stem cell transplant who do not have a matched related donor or matched unrelated donor Study Of Disease Progression And Treatment Of Patients With Polycythemia Vera (PV)Feasibility of CPI-613 for Acute Myeloid LekumiaA study to evaluate the test drug (Imetelstat) in blood transfusion dependent patients with Low or Intermediate Risk Myelodysplastic Syndrome. Testing an Online Intervention to Encourage Healthy Coping and Positive MoodsA Phase IB/II Multi-Arm Study with Venetoclax in Combination with Cobimetinib and Venetoclax in Combination with Cobimetinib and Indasanutlin in Patients Aged > 60 years with Relapsed or Refractory Acute Myeloid Leukemia who are not Eligible for Cytotoxic TherapyA Study to Compare the Combinations of Nivolumab, Elotuzumab, Pomalidomide, and Dexamethasone in Patients with Multiple MyelomaAn observational study evaluating Hemophilia A patients who have previously received Kovaltry for prophylaxis Study Comparing Daratumumab, Lenalidomide, Bortezomib, and Dexamethasone (D-RVd) Versus Lenalidomide, Bortezomib, and Dexamethasone (RVd) in Subjects With Newly Diagnosed Multiple MyelomaPhase 1b/2 study testing radium-223 dichloride in relapsed multiple myelomaMeasuring Quality of Life among Teens and Young Adults with CancerDeveloping and Testing an Electronic Fertility Preservation Decision AidCancer: Leukemia +
A Phase 3 Open-label, Multicenter, Randomized Study of ASP2215 versus Salvage Chemotherapy in Patients with Relapsed or Refractory Acute Myeloid Leukemia (AML) with FLT3 Mutation Cancer: Lung +
Genetic Testing For Patients with Resectable or Resected Lung Cancer Testing whether or not a drug that is known to “target” a certain kind of lung tumor works in patients with that type of tumor Testing the Addition of a Drug After Surgery to Remove ALK-Positive Non-Small Cell Lung CancerStudy of the Effects of an Experimental Drug in Combination with Chemoradiotherapy to Treat Lung CancerA Study Looking at a Drug to Treat Stage 4 Lung CancerImmune Response in Patients with Recurrent or Metastatic Non-Small Cell Lung CancerA Pilot Study of Changes in Circulating Tumor-Specific DNA in Patients with Non-Metastatic Non-Small Cell Lung CancerA Study of Radiation Therapy for people with painful bone metastasisA Study to Evaluate How Well Certain Types of Cancer Respond to an Investigational Drug (LOXO-101)Study comparing the efficiacy of experimental drug, Plinabulin, with docetaxel verses docetaxel with placebo in patients with non small cell lung cancer with at least 1 large lesion.A Study to Determine the Most Effective Sequence of Treatment with Pembrolizumab abd Standard of Care Chemotherapy in Patients with Non-Small Cell Lung CancerA Randomized Study of Radiosurgery with or without Tumor Treating Fields (TTFields) for 1-10 Brain Metastases from Non-Small Cell Lung CancerStudy of Surgical Removal vs. Radiation Therapy for Early Stage Lung CancerCancer: Melanoma +
A Comparison of the Effects of Commerical Drugs Alone or in Combination with an Experimental Immunotherapy Drug for MelanomaA study comparing the outcome of advanced skin Melanoma cancer treated with a test drug given locally into the affected area versus standard of care treatments.Cancer: Myeloproliferative Neoplasms +
A study to test intravenous PRM-151 for safety and to see how different doses of PRM-151 act in the body and blood of people with myelofibrosis - a disorder of the bone marrow, in which the marrow is replaced by scar (fibrous) tissue.Cancer: Other +
Clinical Trial for subjects with non-small cell lung cancer, melanoma, colorectal cancer, squamous cell carcinoma of the head and neck, B-cell Non-Hodgkin lymphoma, or Hodgkin Lymphoma, or GlioblastomaProject: Everychild Biology and Registry StudyCancer: Pediatrics +
Post-Radiation Chemotherapy in Patients with Newly Diagnosed Ependymoma Low-Dose Tamoxifen For Radiation-Induced Breast Cancer Risk ReductionTesting Brentuximab Vedotin at a treatment for Hodgkin's Disease in childrenGanitumab for Newly Diagnosed Metastatic Ewing SarcomaDermatology/Skin Diseases +
Oral Psoriasis Treatment Adherence and Intervention StudySTUDY TO EVALUATE THE SAFETY AND EFFICACY OF AN INVESTIGATIONAL DRUG IN ADULT PATIENTS WITH MODERATE TO SEVERE ALOPECIA AREATAA Phase 2, Randomized, Double-blind, Placebo-controlled Study to Assess the Safety and Efficacy of Filgotinib and GS-9876 in Female Subjects with Moderately-to-Severely Active Cutaneous Lupus Erythematosus (CLE) Epilepsy +
Evaluation and Stimulation of Hippocampal Neuronal Ensembles in Patients Undergoing Intracranial Monitoring for Medically Refractory Epilepsy Cannabidiol for Treatment Resistant Epilepsy in Tuberous Sclerosis PatientsAn Open-Label Study to Evaluate Perampanel (E2007) Oral Suspension When Given as an Adjunctive Therapy in Subjects From 1 Month to Less Than 24 Months (<2 years) of Age With EpilepsyEye +
Abicipar Pegol In Patients with Neovascular Age-related Macular DegenerationGastrointestinal Diseases +
Understanding GastroparesisNatural History of Acute Hepatic Porphyria Patients with Recurrent AttacksA study comparing biologic agents in patients with Ulcerative Colitis or Crohn's DiseaseEffect of Oral Iron Therapy on Erythrocyte Protoporphyrin Levels in the Erythropoietic ProtoporphyriasNewer Direct-Acting Anti-Viral Agents as Sole Therapy of Porphyria Cutanea Tarda in Subjects with Chronic Hepatitis CA Study to Monitor the Use of an Amino Acid-Based Infant FormulaGenetic Disorders +
Studies of the Variable Phenotypic Presentations of Rapid-Onset Dystonia-Parkinsonism and Other Movement DisordersCharacterization of Individuals with Fanconi SyndromeGrowth & Hormones +
Study to compare two treatment options for benign prostatic hyperplasia (BPH) A Phase 2A, Double Blind, Placebo controlled study of RSLV-132 in subjects with Systemic Lupus Erythematosus (SLE)Healthy Volunteers +
Screening for Fatty Acid Processing Gene Variants in Healthy AdultsBrain processes involved in the effects of mindfulness meditation and painPAIN PERCEPTION AND STRESS REDUCTION FOR MIGRAINES MILES (Microbiome Insulin Longitudinal Evaluation Study)Identifying Heart Damage with a MRI ScanHeart Disease +
HEART Pathway Randomized Controlled TrialSurgical Replacement and Transcatheter Aortic Valve Implantation - Single arm studySTRENGTH STUDY-Study of the effects of an investigational omega 3 fatty acid treatment on the reduction of heart problems. Specimen Collection for the Assessment of Troponin AssaysStudying the Use of Transcatheter Aortic Valve Replacement for Patients with Symptomatic Aortic Stenosis.Evaluation of new medication for heart failure.Study of the Effects of Caloric Restriction and Exercise TrainingBlood Test to Aid With Diagnosing Acute Heart FailureDal-Gene StudyTranscatheter Aortic Valve Replacement With the Medtronic Transcatheter Aortic Valve Replacement System In Patients at Low Risk for Surgical Aortic Valve ReplacementPIONEER-HF: Sacubitril/Valsartan vs. Enalapril following Acute Decompensated Heart FailureGetting to an improved Understanding of Low-Density Lipoprotein Cholesterol and Dyslipidemia Management a Registry of High Cardiovascular Risk Subjects in the United States: The GOULD StudyA Randomized Study to Assess the Effects of Bempedoic Acid on the Occurrence of Cardiovascular Events in Patients with, or at High Risk For, Cardiovascular Disease who are Statin Intolerant.Cardiac Blood Test to Optimize Chest Pain Risk StratificationEffects od Dapagliflozin on biomarkers, symptoms and functional status in patients with type 2 diabetes or pre-diabetes, and preserved ejection fraction heart failure (PRESERVED-HF TRIAL)Study to determine the safety and dose-response of an FDA approved medication in patients, 45 and older, with heart failure symptoms and normal heart pumping function. Study of the Effects of HIRREM on Stage One Primary HypertensionKidney/ Liver Disease +
Inherited Kidney DiseaseStudy of Childhood Onset Nephrotic SyndromeStudy of how a new anemia drug, daprodustat, compares to darbepoetin alfa.Lung Disease +
Study of the Effects of dasatinib and quercetin on IPFPreliminary study for comparison of triple therapy nebulizer versus dry powdered inhaler for care transitions in COPDMemory +
Alzheimer’s Disease Prevention Participant Repository (ADPPR)SNIFF QuickThe A-4 StudyResearch Cognitive Assessment StudyTherapeutic Effects of Exercise in Adults with Mild Memory ImpairmentMenopause +
Study of the Effect of HIRREM on Hot FlashesMental Disorders +
Evaluation of the Safety and Efficacy of Levomilnacipran ER in Adolescent Patients with Major Depressive DisorderTranquil Moments IIMovement Disorders +
Open-Label Study of the Effects and Safety of APL-130277 in Patients with Parkinson’s Disease Experiencing “OFF” EpisodesPhenotype, genotype, and biomarkers (PGB) in ALS and related disordersObesity +
A study to look at movement to prevent obesity and weight regain (EMPOWER)Weight Loss in Pre-diabetics (VEGGIE)Pain +
Clinical Pain RegistryStudy of the Effects of Botox on Chronic Testicular PainStress Reduction for MigrainesPediatrics +
Post-Radiation Chemotherapy in Patients with Newly Diagnosed Ependymoma Low-Dose Tamoxifen For Radiation-Induced Breast Cancer Risk ReductionTesting Brentuximab Vedotin at a treatment for Hodgkin's Disease in childrenGanitumab for Newly Diagnosed Metastatic Ewing SarcomaStudy of the Safety and Efficacy of oral Dabigatran Etexilate for the prevention of recurring Venous Thromboembolism Stroke +
Study of the Effects of Intranasal Insulin Spray on Memory after a Mild StrokeBiomarkers for Acute Stroke Etiology (BASE)Stroke Prevention Study Comparing the Efficacy and Safety of Pradaxa (Dabigatran) to Aspirin in Patients with Embolic Stroke of Undetermined Source (ESUS)Vascular Disorders +
Endovascular Graft Clinical Study Patient Preferences in the Treatment of Critical Limb Ischemia (rest pain and non-healing wounds)A Pilot Study of Cilostazol to Improve Quality of Life.Trial to compare best endovascular versus best surgical therpay in patients with Critical Limb Ischemia Framing Eighteen Coils in Cerebral Aneurysms TrialStudy for Myasthenia Gravis to Collect Blood to Check for AntibodiesCREST 2. Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis TrialAn observational study evaluating the safety of an FDA approved drug, Obizur, in patients with hemophilia A.Women's Health +
Endometriosis: Mechanisms of Pain and InfertilityPain in Women Who Have Had a BabyRandomized Trial Comparing Vaginal Laser Therapy to Vaginal Estrogen Therapy (VeLVET)Leadership 301 studyOther +
Patients who have passed-out or almost passed -out.Effects of Vitamin D on ARDSHypoglycemic Symptoms Study for those who regularly have symptoms of low blood sugar (hypoglycemic symptoms), but do not have diabetes. Study of Topical ABI-1968 in Subjects With Precancerous Anal Lesions Resulting From Human Papillomavirus (HPV) Infection

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